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Treatment of deficiency Supplementation with B 12 is conducted to treat deficiency either orally (if vegan diet) or parenterally (if atrophy gastritis)
The idea is supported by maintenance of functional GSH/GSSG levels by Sp in BSO and neurotoxin treated cells as compared to untreated ones which showed a significant decline in the antioxidant ratio probably, due to enhanced formation of glutathionequinones 43
Riedl et al., Clin Immunol, 2009) [27][28]
But research protocols sometimes call for non-standard doses
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